The nematode worm Caenorhabditis elegans has become an important model organism in the scientific world. This is partly because of its sequenced genome, transparent embryo and adults, ease of carrying out genetic analyses, 3-day life cycle, complete lineage map of the total 959 cells, complete wiring diagram of the nervous system with all 302 neurons and their interconnections. Studies of C. elegans have lead to many important discoveries, including programmed cell death and RNA interference, as well as useful applications, such as visualizing gene expression using green fluorescent protein (GFP). The C. elegans core facility (CECF) was founded in 2007. The number of labs in Taiwan studying C. elegans has been increased by a factor of 10s since then. The goals of CECF are to increase scientific awareness about this important model organism and to promote C. elegans research in Taiwan.